Get tested and get the results you need to move forward

Alpha-1 is a progressive disease, which means that it can worsen over time and cause more damage to your lung function if left undiagnosed and untreated.1

Getting tested for Alpha-1 is the first step toward better understanding your lung disease and overall health and receiving appropriate treatment.

Alpha-1 can only be diagnosed by a blood test

There are many ways that other serious lung disorders can be diagnosed by your doctor. When testing for other serious lung diseases, your doctor may:

  • Measure the ability of your lungs to take in air
  • Take an X-ray to look at the condition of your lungs
  • Listen to your breathing with a stethoscope

These are all tests and observations that your doctor performs to evaluate the physical symptoms of lung disease.

However, because the symptoms of Alpha-1 are often identical to those of other common disorders, an accurate diagnosis of Alpha-1 based on clinical presentation alone is not possible.6 An accurate diagnosis can only be achieved by taking a blood test.

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Get advanced testing

DNA1 Advanced Alpha-1 Screening™

DNA1 Advanced Alpha-1 Screening is a free and easy-to-use Alpha-1 test that can identify Alpha-1 genes and variants that other tests may miss.10

DNA1 Advanced Alpha-1 Screening delivers comprehensive test results and provides educational materials to help you and your doctor through an Alpha-1 diagnosis.

Our DNA1 Advanced Alpha-1 Screening Test Kit offers targeted genotyping and next-generation gene sequencing without the need for additional testing.

The DNA1 test helps rule out whether your A1AT levels may be higher than normal due to sickness or inflammation. Additionally, DNA1 uses an advanced technique called “isoelectric focusing” to help verify any generic variations that may be identified during your genetic test.

Targeted genotyping

  • DNA1 looks beyond the most common gene alleles to identify cases involving rare variants that other tests can’t detect

Next-generation sequencing of the SERPINA1 gene

  • DNA1 provides complete next-generation genetic sequencing of the SERPINA1 gene to identify known and previously undiscovered variants
  • Sequencing of the SERPINA1 gene helps identify all Alpha-1 patients and carriers, even if they have a rare gene
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Early testing and diagnosis can help you and possibly your family members receive appropriate treatment and elevate levels of alpha-1 antitrypsin in your body.

How do I get tested using the DNA1 Advanced Alpha-1 Screening test?

  • Order your free test and take it to your next doctor’s appointment
  • Your doctor or nurse will administer the test and send it to the lab to get results
  • Test results will be sent from the lab to your doctor
  • Your doctor will contact you when your test results are received
  • If your test results show that you have Alpha-1, your doctor will talk to you about appropriate treatment
  • Your doctor will also provide you with information about genetic counseling and living with Alpha-1

With DNA1 Advanced Alpha-1 Screening, there is typically no need to retest

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