Important Safety Information Prescribing Information For Healthcare Professionals | For Patients

Clinical Data

Raise your A₁AT protein levels with ZEMAIRA

Explore more about your Alpha-1 journey

ZEMAIRA has been proven to raise and maintain serum levels of A₁AT protein.¹³

When administered once a week for 24 weeks at a dose of 60 mg per kg of body weight, patients with Alpha-1 saw a rapid increase in A₁AT levels that were maintained throughout the study period.¹³

Clinical data demonstrating the long-term effects of chronic augmentation therapy with ZEMAIRA are not available.

ZEMAIRA Purity

ZEMAIRA is made in a state-of-the-art facility under strict, controlled conditions, and is purified from human plasma through a rigorous virus-removal and inactivation process. Because ZEMAIRA is made from human blood, the risk of transmitting infectious agents cannot be completely eliminated.

Safety

Studies have shown that A₁AT augmentation therapy is safe.

In clinical studies of ZEMAIRA, at least 5% of subjects reported adverse reactions related to treatment, including:

Headache
Sinusitis
Upper respiratory infection
Bronchitis
Fatigue
Increased cough
Fever
Injection-site bleeding
Nasal symptoms
Sore throat
Swelled blood vessels

Dosing and Administration

Dosing

The recommended dose of ZEMAIRA is 60 mg/kg body weight given once weekly

Administration

ZEMAIRA is administered into your vein at a dose recommended by your doctor
The recommended dose should take approximately 15 minutes to infuse, but this may vary as the dose is based on your current weight
ZEMAIRA can be stored safely at room temperature
Your dose will need to be mixed before administering. Your doctor or pharmacist will explain how

Get started on ZEMAIRA therapy without delay and without disruption

Enroll online or call ZEMAIRA CareZ^® to speak with an experienced CareZ Care Coordinator. Call 1-866-ZEMAIRA (1-866-936-2472) and learn more.

Enroll online and get started on ZEMAIRA