Clinical Data

Raise your A1AT protein levels with ZEMAIRA

Explore more about your Alpha-1 journey

ZEMAIRA has been proven to raise and maintain serum levels of A1AT protein.13

When administered once a week for 24 weeks at a dose of 60 mg per kg of body weight, patients with Alpha-1 saw a rapid increase in A1AT levels that were maintained throughout the study period.13

Clinical data demonstrating the long-term effects of chronic augmentation therapy with ZEMAIRA are not available.


ZEMAIRA is made in a state-of-the-art facility under strict, controlled conditions, and is purified from human plasma through a rigorous virus-removal and inactivation process. Because ZEMAIRA is made from human blood, the risk of transmitting infectious agents cannot be completely eliminated.


Studies have shown that A1AT augmentation therapy is safe.

In clinical studies of ZEMAIRA, at least 5% of subjects reported adverse reactions related to treatment, including:

  1. Headache
  2. Sinusitis
  3. Upper respiratory infection
  4. Bronchitis
  5. Fatigue
  6. Increased cough
  7. Fever
  8. Injection-site bleeding
  9. Nasal symptoms
  10. Sore throat
  11. Swelled blood vessels
Couple looking at doctor

Dosing and Administration


  • The recommended dose of ZEMAIRA is 60 mg/kg body weight given once weekly


  • ZEMAIRA is administered into your vein at a dose recommended by your doctor
  • The recommended dose should take approximately 15 minutes to infuse, but this may vary as the dose is based on your current weight
  • ZEMAIRA can be stored safely at room temperature
  • Your dose will need to be mixed before administering. Your doctor or pharmacist will explain how

Get started on ZEMAIRA therapy without delay and without disruption

Enroll online or call ZEMAIRA CareZ® to speak with an experienced CareZ Care Coordinator. Call 1-866-ZEMAIRA (1-866-936-2472) and learn more.

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