My doctor understands Alpha-1

Testing and Diagnosis

The importance of testing

Alpha-1 is underrecognized and frequently misdiagnosed5

  • Less than 10% of people with Alpha-1 have been diagnosed based on expectations set by screening studies in the general population8
  • Alpha1 antitrypsin is an acute-phase reactant, which may cause serum levels to fluctuate, depending on a patient's medical condition9
  • It can take patients about 7 years to receive an accurate diagnosis for this condition10
It has been estimated that more than 90% of those with Alpha-1 are currently undiagnosed or misdiagnosed.8

ATS/ERS Testing Guidelines

Order the Alpha LabZ eZ Kit for Your Office

CSL Behring's new test kit makes it easy to receive prompt, accurate, and thorough test results

Read More

See How Alpha-1 Affects the Lungs

Watch a video animation that shows the critical role of alpha1 antitrypsin in the lungs

Watch Video

Important Safety Information

Alpha1-Proteinase Inhibitor (Human), Zemaira® is indicated for chronic augmentation and maintenance therapy for adults with alpha1-proteinase inhibitor (A1-PI) deficiency and emphysema. Clinical data demonstrating the long-term effects of chronic augmentation therapy with Zemaira are not available.

Zemaira may not be appropriate for the following adult individuals as they may experience severe reactions, including anaphylaxis: individuals with a known hypersensitivity and/or history of anaphylaxis or severe systemic reaction to A1-PI products or their components, and individuals with selective IgA deficiencies who have known antibodies against IgA.

In clinical studies, the following treatment-related adverse reactions were reported in 1% of subjects: asthenia (fatigue), injection-site pain, dizziness, headache, paresthesia (tingling), and pruritus (itching).

Zemaira is derived from human plasma. The risk of transmission of infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent, cannot be completely eliminated.

Please see full prescribing information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

The information provided herein is solely for use by physicians and healthcare professionals in the United States. The CSL Behring product listed may not have been approved in other countries and may not be available everywhere.