Other Supportive Measures

Practical steps you can take to help yourself

In addition to augmentation therapy, there are other things you can do to help you live a healthy lifestyle with Alpha-1.

Quit smoking—If you're a smoker, no other single factor can improve your prospects for survival as much as quitting. Contact your local American Lung Association for smoking cessation programs, or ask your doctor for help^4,7
Avoid respiratory irritants—Try to avoid breathing dust, pollen, pet dander, and fumes, including smoke of any kind.^4,7 Talk with your physician about air purifiers for your home
Avoid infection—Among the most effective ways to minimize the risk of infection are washing your hands frequently and avoiding contact with people who have a cold or the flu. Ask your doctor about pneumonia vaccine and annual flu shots.^4,7 Avoid crowds, especially high-risk environments such as movie theaters, airplanes, hospitals, clinics, schools and daycare facilities. If you must go to a high-risk environment, wear a mask around your mouth and nose.⁷
Exercise daily—Developing an exercise routine with your doctor's input can be critical. If you have lung problems, a pulmonary rehabilitation exercise program is highly recommended. Ask your doctor about this type of program^4,7
Eat healthy—Eating properly may help preserve lung function. Talk with your doctor about finding a nutritionist who can help design a dietary plan that will work for you^4,7
Reduce stress—Choose from a wide variety of stress-reducing activities, including breathing exercises, meditation, and yoga^4,7
Use inhalers—Metered-dose inhalers and inhaled corticosteroids may provide temporary relief of symptoms. Be sure to follow your doctor's instructions when using these prescription therapies⁷

The Zemaira Difference

Connect to CareZ™

A community that offers comprehensive support services for patients with Alpha-1

Do I Have Alpha-1?

A simple questionnaire that encourages patients to talk to their doctor about getting tested for Alpha-1

Important Safety Information

Alpha₁-Proteinase Inhibitor (Human), Zemaira^® is indicated for chronic augmentation and maintenance therapy for adults with alpha₁-proteinase inhibitor (A₁-PI) deficiency and emphysema. Clinical data demonstrating the long-term effects of chronic augmentation therapy with Zemaira are not available.

Zemaira may not be appropriate for the following adult individuals as they may experience severe reactions, including anaphylaxis: individuals with a known hypersensitivity and/or history of anaphylaxis or severe systemic reaction to A₁-PI products or their components, and individuals with selective IgA deficiencies who have known antibodies against IgA.

In clinical studies, the following treatment-related adverse reactions were reported in 1% of subjects: asthenia (fatigue), injection-site pain, dizziness, headache, paresthesia (tingling), and pruritus (itching).

Zemaira is derived from human plasma. The risk of transmission of infectious agents, including viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent, cannot be completely eliminated.

Please see full prescribing information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.